MOESM1 of Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects

Juan Yu, Lei Wang, Pei Pei, Xue Li, Jianxin Wu, Zhiyong Qiu, Juan Zhang, Ruifang Ao, Shan Wang, Ting Zhang, Jun Xie
2019 Figshare  
Additional file 1: Figure S1. Bioinformatic analysis of RNA-seq. A. Morphology of mouse NTDs embryos induced by RA. (a). Normal mouse embryo. (b). Mouse embryo showed growth retardation, neural tube close incompletely. Arrow indicates unclosed neural tube. (c). Mouse embryo showed anencephaly, enlarged heart and ventricular chambers, and short tail. Arrow indicates hindbrain, heart and tail respectively. B. Unsupervised hierarchical clustering plot of genes detected in mouse embryo cranial
more » ... embryo cranial neural tissue. C. GO functional classification of DEGs. Blue represents cellular component, red represents molecular function, and green represents biological process. D. KEGG pathway analysis of DEGs. E. Protein-protein interaction (PPI) network of 196 genes analyzed by STRING database.
doi:10.6084/m9.figshare.11415591.v1 fatcat:apgp4cbpobdrtld3bze63je3ae