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Monoclonal antibodies in the treatment of sepsis caused by Gram-negative microorganisms
Los anticuerpos monoclonales en el tratamiento de la sepsis provocada por microorganismos gramnegativos
1998
Revista Cubana de Medicina Tropical
Los anticuerpos monoclonales en el tratamiento de la sepsis provocada por microorganismos gramnegativos
In spite of the advances attained in the diagnosis and early intervention with antibiotics, morbidity and mortality associated with sepsis caused by Gram-negative bacteria are high. The mediators responsible for the pathogenesis of the sepsis are components derived from the own bacteria (endotoxins) and from the cells of the immune response of the host (tumor necrosis factor and some interleukins). The treatment traditionally used in sepsis is mainly directed against microorganisms by the use
pmid:9842265
fatcat:ei2dhni6wnayzh34jlgy7z633a