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Authors report two cases of regional anesthesia management whom were scheduled for total hip replacement surgery due to ankylosing spondylitis.Methods: Mouth opening, and cervical spine movements were limited. Cervical ostheophytes have been recognized to cause distortion of the airway and can lead to unexpected difficulties during intubation.Results: In present first case report we described continuous spinal anesthesia for a patient with severe ankylosing spondylitis. We achieved successfuldoi:10.18203/2349-2902.isj20183214 fatcat:lpvesy7tbnbf3epjtu24jqscni