Flavone glucosides from Artemisia juncea

Bakhodir S. Okhundedaev, Markus Bacher, Rimma F. Mukhamatkhanova, Ildar J. Shamyanov, Gokhan Zengin, Stefan Böhmdorfer, Nilufar Z. Mamadalieva, Thomas Rosenau
2018 Figshare  
A new flavone glucoside, 4′,5-dihydroxy-3′,5′,6-trimethoxyflavone-7-O-β-D-glucoside was obtained from aerial parts of Artemisia juncea, together with the known flavone eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone). The compounds were comprehensively analytically characterized by IR, UV, NMR and HR-MS, and their chemical structures ascertained. The EtOAc fraction of A. juncea showed the strongest DPPH radical scavenging ability as well as reducing power (in CUPRAC and FRAP assays) and
more » ... AP assays) and phosphomolybdenum activity. This fraction also exhibited the strongest inhibitory effects on tyrosinase. Additionally, the best antidiabetic effects were observed for eupatilin and the CHCl3 fraction.
doi:10.6084/m9.figshare.7335035.v1 fatcat:dcd7zr5vzveqjpqpuscissabq4