Mesenchymal and trophoblast immunophenotype of multipotent stromal cells from human placenta

V. A. Shablii, M. D. Kuchma, V. M. Kyryk, H. M. Svitina, Yu. M. Shablii, L. L. Lukash, G. S. Lobintseva
2014 Biopolymers and Cell  
Aim. The investigation of trophoblast markers expression in the mesenchymal stromal cells of placental tissue before and after their isolation and cultivation. Methods. Placental multipotent mesenchymal stromal cells (MMSC) were obtained by culturing the adhesive fraction of cells enzymatically isolated from the placental tissue. The placental derived cells were immunophenotyped by flow cytometry and immunocytoche-mistry. Results. It was shown that the placental MMSC express the trophoblast
more » ... the trophoblast markers: are presented in the placental tissue. Conclusions. The placental MMSC simultaneously express mesenchymal and trophoblast markers.
doi:10.7124/bc.000889 fatcat:o37vczw3azhhnge2mhnywd4k6e