MOESM18 of Transient reduction of DNA methylation at the onset of meiosis in male mice

Valeriya Gaysinskaya, Brendan Miller, Chiara Luca, Godfried Heijden, Kasper Hansen, Alex Bortvin
2018 Figshare  
Additional file 18: Figure S10. Genome-wide relationship between replication timing and DNA methylation. (A) Replication timing (RT) data from CH12 cells (mouse B cell lymphoma) [71] were correlated with CpG DNA methylation corresponding to late RT domains. Note a prominent switch in correlation directionality from PL to L. Biological replicates (Reps 1 and 2) were processed individually and are shown in light and dark red. (B) The PL cell fraction enriched by FACS contains replicating cells.
more » ... eplicating cells. More than 70% of FACS-enriched PL cells are EdUâ +â , enriched in mid- and late- S phase, based on the characteristic EdU staining patterns.
doi:10.6084/m9.figshare.6094388 fatcat:5xv5eihtxbcahkckaap7w2tnqy