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Aim:To assesses the efficacy of a relatively new drug-Febuxostat in management of gout and its comparison with allopurinol. Method: A comparative study of both Allopurinol and Febuxostat was done on 100 patients of gout. Both were studied for ef ficacy. side effects and for gout flare up. Results: Primary efficacy end point (baseline values) -a serum urate concentration of less than 6.0mg per deciliter at the last three measurements was reached by 54 %( 27/50) of group A patients taking 80mgsdoi:10.3329/bjms.v10i4.7522 fatcat:25ftn4wzfze2lekd67btmqqisu