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The serum concentrations oflactoferrin were determined by competi tive enzyme immunoassay in the sera of 38 lepromatous leprosy patients and 16 healthy volunteers. Of the 38 lepromatous patients, 25 were without any sign of reactions while 13 were suffering from EN L type of reactions. The lactoferrin levels, in both types of patients, were observed to be significantly higher'(P < 0·0 I and < 0·00 I, respectively) than in that of healthy volunteers. The rise in lactoferrin level in reactivedoi:10.5935/0305-7518.19930033 fatcat:mtu67ido6rg7dfbhgw7ciaj7gi