Phylogenetic analysis of the emergence of main hepatitis C virus subtypes in São Paulo, Brazil

Anna Shoko Nishiya, César de Almeida-Neto, Camila Malta Romano, Cecília Salete Alencar, Suzete Cleusa Ferreira, Claudia Di-Lorenzo-Oliveira, José Eduardo Levi, Nanci Alves Salles, Alfredo Mendrone-Junior, Ester Cerdeira Sabino
2015 Brazilian Journal of Infectious Diseases  
b r a z j i n f e c t d i s . 2 0 1 5;1 9(5):473-478 intermediate growth rate (r = 0.32). An evident exponential growth (r = 0.26) was found for hepatitis C virus-1b between 1980 and the mid-1990s. Conclusions: After an initial period of exponential growth, the expansion of the three main subtypes began to decrease. Hepatitis C virus-1b presented inflated genetic diversity, and its transmission may have been sustained by different generations and transmission routes other than blood
more » ... n blood transfusion. Hepatitis C virus-1a and -3a showed no group stratification, most likely due to their recent entry.
doi:10.1016/j.bjid.2015.06.010 pmid:26296325 fatcat:qtry4e745bbk7j2qj5wadui4wm