An unusual course of disease in two patients with COVID-19: pulmonary cavitation

Michael Muheim, Fabio José Weber, Patrick Muggensturm, Eva Seiler
2020 BMJ Case Reports  
Two 59-year-old male patients with COVID-19 pneumonia developed pulmonary cavitation with air-fluid level, accompanied by right-sided chest pain several weeks after first onset of symptoms. Considering a possible bacterial abscess formation, both patients were started on antibiotics. No microbiological pathogen was detected in further investigations (sputum analysis, bronchoscopy with bronchoalveolar lavage and CT-guided drainage of the cavitation). Histopathological analysis of the drained
more » ... d was non-specific, and the aetiology remained not fully understood. We report pulmonary cavitation as a rare finding in late stage COVID-19 pneumonia. As both our patients presented with localised chest pain prior to detection of the lesions, new onset of this symptom should warrant further investigation.
doi:10.1136/bcr-2020-237967 pmid:32900753 fatcat:ymxhx7xmgbej7b4etkdkberuy4