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Objective: To discuss the genetic basis of occlusal traits through analysis of the effects of inbreeding in a subdivided isolated community. Subjects and methods: The sample comprised dental casts of 224 children, aged 7-14 years, from 15 villages of the Island of Hvar, Croatia. Main outcome measures: Studied traits were Angle class, overjet, vertical bite, overbite, and crowding/spacing. Design: Children with complete grandparental endogamy (all four grandparents born in the village ofdoi:10.1093/ortho/30.4.301 pmid:14634168 fatcat:4jd5cvydtvcelgsqmc6fqdzw3a