A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf
.
Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks
2012
BMC Systems Biology
Identification of essential proteins plays a significant role in understanding minimal requirements for the cellular survival and development. Many computational methods have been proposed for predicting essential proteins by using the topological features of protein-protein interaction (PPI) networks. However, most of these methods ignored intrinsic biological meaning of proteins. Moreover, PPI data contains many false positives and false negatives. To overcome these limitations, recently many
doi:10.1186/1752-0509-6-87
pmid:22808943
pmcid:PMC3472210
fatcat:l6mgjpbbubbihcry462oalwymi