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Lipase Rice Bran Design Expert A B S T R A C T Among enzymes, lipases have been widely investigated because of their numerous industrial applications. In this study, optimization of lipase production by Aspergillus niger in solid state fermentation from rice bran as solid substrate was investigated. The optimal conditions were obtained with the aid of central composite design (CCD) under response surface methodology (RSM). In the analysis of 20 experimental runs, effects of three variables suchdoi:10.5829/idosi.ije.2012.25.03b.01 fatcat:k4hixcone5btjf4xlqwk7ubnri