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Houghton1 reports a case in which the treatment was more radical. The patient was a man, 69 years old, with symptoms and physical signs of pernicious anemia, hemoglobin 45 per cent. Unfortunately, the reds were not taken. A differential showed a relative lymphocytosis with many normoblasts. The urine was albuminous and contained casts, and the skatol and indican reaction was marked. Arsenic and colonicdoi:10.1001/jama.1909.25420370047004h fatcat:2p7wwmrx2ngthidbppdwu4uo2m