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Craniosynostosis syndrome is characterized by premature craniosynostosis occurring in association with a variety of other abnormalities. The most common craniosynostosis disease occurring without syndactyly is craniofacial dystosis or Crouzens syndrome. Most common craniosynostosis disease occurring with syndactly is Apert's syndrome. Apert's syndrome is characterized by craniosynostosis, midfacial malformations, symmetric syndactyly of hands and feet minimally involving digit second, third anddoi:10.5005/jp-journals-10011-1236 fatcat:dcrwakw6x5elrjp7u5h67zzohu