Littoral cell angioma mimicking metastatic tumors

Justyna Szumilo, Anna Ostrowska, Malgorzata Zdunek, Slawomir Rudzki, Tomasz Chroscicki, Elzbieta Czekajska-Chehab, Franciszek Burdan
2015 Current Issues in Pharmacy and Medical Sciences  
Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the "littoral cells"). It is a benign, usually asymptomatic lesion diagnosed incidentally. Ultrasound and tomography appearance is not characteristic and histopathological examination is required. This work provides a case-study of littoral cell angioma which was seen in a 55-year-old female who complained of non-specific upper abdominal pain.
more » ... dominal pain. Computed tomography revealed multiple hypo-attenuated splenic lesions suggestive for metastasis. A splenectomy was performed and routine microscopic examination supported by immunohistochemistry reactions with CD68, CD34 and CD31 showed littoral cell angioma.
doi:10.1515/cipms-2015-0081 fatcat:5chmmxz3qjaxvo34pv5pijqbvi