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Pulmonary arteriovenous fistula is a rare disease with a direct connection between the pulmonary artery and the vein, and in most cases is congenital. In a proportion of patients, it can cause hypoxemia, cyanosis and dyspnea. The golden standard for the diagnosis of PAVF is pulmonary angiography. We experienced two cases of a daughter and a mother with PAVF diagnosed by contrast echocardiography, which is simple and sensitive for the detection of pulmonary arteriovenous fistula. Casedoi:10.21203/rs.3.rs-16024/v1 fatcat:x2ziqodpzvfhtlmz4e5k3hxnvq