BSE is simple, non-invasive, requires little time and cost free practice and it can be perform by both young and old women. By performing BSE can recognize changes, such as thickening, lumps, spontaneous nipple discharge or skin change, and dimpling. However, the women who not perform BSE are high risk for breast cancer. Breast cancer is the second most frequent occurring cancer among women. Objective: The object of this study to assess the knowledge, attitude and practice of BSE among female

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... dergraduate CMHS, university of Gondar student's. Methods: An institution based cross sectional study design was conducted at the University of Gondar, collage of medicine and health science from April to June 2018. A total of 300 students were included in this study. The source population was all female undergraduate nursing students. The study was selected by simple random sampling technique. Selfadministered questionnaire was used for data collection. Then data was entered to Epi info version 3.5.4. The enter data was export to SPSS statistical package for analysis. Result: In this study, a total of 300 undergraduate female nursing students participated in the study and giving a response rate of 100% About knowledge of the female undergraduate students with regard to BSE is found to be 55.7% with 95% CI: (56-61%) had knowledge of breast self examination while 176 (56.7%) with 95% CI: (53-64%) of the female undergraduate students have favorable attitude about BSE. Of the total participants, 34 (11.3%) with 95% CI: (7-15%) of the female undergraduate students had practiced Conclusion: In general, the KAP of the participants were, 55.7% with 95% CI: (56-61%), 56.7% with 95% CI: (53-64%) and 11.3% with 95% CI: (7-15%) respectively. This finding showed that the participants had poor KAP toward BSE. Therefore, Universities and other stake holders should plan to promote provision of information, education and communication targeting females, and the general community to increase awareness to ward breast self examination.