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The Study of Genetic Factors Involved in Diet-induced Dysfunction of Glucose and Lipid Metabolism
Nippon Eiyo Shokuryo Gakkaishi
Type diabetes and fatty liver are multiple factor diseases controlled by both environmental and genetic factors. To reveal the gene s involved in common diseases caused by interaction with dietary factors, we performed genetic analyses using an animal model in which both environmental and genetic factors were strictly controlled. First, in mouse SMXA recombinant inbred strains, we demonstrated that interaction between latent susceptible genes led to development of type diabetes and fatty liver.doi:10.4327/jsnfs.67.283 fatcat:w3srnttto5dbrcjxowbp2u7zha