The pathophysiology of prediabetes (impaired fasting glucose and impaired glucose tolerance) still to be clearly understood as. The present study was undertaken to determine genotype of Vitamin D receptor (VDR) gene Bsm1 (A>G) and Fok1 (C>T) polymorphic allele in a group of impaired glucose tolerance (IGT) subjects of Bangladeshi origin and investigate its association with insulin sensitivity and cell secretory capacity. i) VDR gene Bsm1 (A>G) and Fok1 (C>T) polymorphic alleles are not

more »

... d with IGT of Bangladeshi origin. ii) The polymorphic marker alleles did not have any effect on fasting and two hour blood glucose and insulinemic status of the IGT and Controls iii) The study reconfirmed that insulin sensitivity is predominantly present in the IGT subjects of Bangladeshi origin.