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Platycodongrandiflorus (PG) root extract has been widely used as an oriental herbal medicine. Red PG root extract (RPGE), which is made by steaming and drying PG several times, contains more saponin than raw (white) PG. Although RPGE has been known to have anti-inflammatory activity, the effects of RPGE on the immune-enhancing response remain unclear. In this study, we aimed to investigate the immune-enhancing effects of RPGE and its mechanism in macrophage cells and splenocytes. Our resultsdoi:10.3390/app10165457 fatcat:2b6n4blq7zabjij4go5og22z4i