A Review on Hydroxychloroquine Drug: to Combat COVID-19

2020 Letters in Applied NanoBioScience  
The drug hydroxychloroquine is an efficacious drug for the treatment of various ailments of the human. This drug is used to Malaria, Rheumatic Arthritis, Systemic lupus erythematosus, and other liver ailments. It increases the lysosomal pH of the molecule and produces an acidic environment. So as to reduce the toxicity of the cell. COVID-19 is a pandemic and emerging disease across the globe, which is devastating to the human population. As a remedial measure, hydroxychloroquine drug can be
more » ... ine drug can be used as an effective measure for the treatment of COVID-19. The mechanism of hydroxychloroquine includes inhibition of cytokine production and signaling pathways, which also gives cellular and cardiovascular effects. The recent steps and procedures taken by the countries to use hydroxychloroquine as an effective drug against COVID-19 are also discussed. As hydroxychloroquine is a derivative of chloroquine shows a more efficacious effect on COVID-19, but as a traditional drug, chloroquine causes more damage as compared to its derivative. Thus we conclude that the emerging disease COVID-19 can be constrained by the use of this efficient drug.
doi:10.33263/lianbs94.17051716 fatcat:vra724dw5bc6dfr6lo3sxiq6pm