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We investigated the potential of fluorescence molecular tomography to imageex vivosamples collected from a large animal model, in this case, a dog spine. Wide-field time-gated fluorescence tomography was employed to assess the impact of multiview acquisition, data type, and intrinsic optical properties on the localization and quantification accuracy in imaging a fluorescent inclusion in the intervertebral disk. As expected, the TG data sets, when combining early and late gates, providedoi:10.1155/2012/942326 pmid:23197973 pmcid:PMC3503328 fatcat:lacsomqs2rczren7udn23i2wuu