1910 Journal of the American Medical Association  
importance) making an upen door for a bacterial inva¬ sion. "A scarification produced by rotary movements is more advantageous than scarification by incisions, as it gives a very small superficial wound." ' These advan¬ tages of the drilling method, emphasized by Von Pirquet in his cutaneous tuberculin test, hold equally good of the ordinary vaccinal ion. With this new method, only a single trauma! ic circumscribed lesion is formed. A minimum of vac-cine material is used, and an almost
more » ... ally circular pustule ripens sharply. A crust is Formed and covers the underground completely and cover and contents dry down slowly without breakingthe main issue in any uneventful vaccination.
doi:10.1001/jama.1910.04330120020007 fatcat:qvlflp7edfaevj3d4jcnkqzdj4