The Synthesis and X-ray Studies of 6-pyrrolidinyl-2-triazolyl Purine Arabinonucleoside

Irina Novosjolova, Ērika Bizdēna, Sergey Belyakov, Māris Turks
2013 Materials Science and Applied Chemistry  
C(6)-Pyrrolidinyl derivative with triazolyl moiety at C(2)-position was obtained from 2,6-bis-triazolylpurine arabinonucleoside via C(6)-regioselective nucleophilic substituon of 1,2,3-triazolyl moiety with pyrrolidine. The obtained compound was studied by NMR, X-ray, UV/VIS and emission spectra. Pyranose form of arabinose residue and α-configuration of the obtained compound were unambiguously proven by NMR and X-ray studies.
doi:10.7250/msac.2013.007 fatcat:wpzknl7yvrdjvd5oi2xm44qfjy