CHRONIC KIDNEY DISEASE; THE ASSOCIATION OF PLATELET COUNT WITH ESTIMATED GLOMERULAR FILTRATION RATE IN KNOWN CASES
English

Dr. Shagufta Memon, Dr. Navaid Kazi, Dr. Amin Fahim, Dr. Ghulam Shah Nizamani, Prof. Dr. Anila Qureshi
2016 The Professional Medical Journal  
ABSTRACT... Objectives: This study aimed to determine the platelet count in diagnosed chronic renal failure patients and to find out the association of platelet count with glomerular filtration rate. Study Design: Case control study. Place of study: Diagnostic and research laboratory Liaquat University Hospital Hyderabad and Nephrology Unit, Isra University Hospital Hyderabad. Duration of study: January 2015 to July 2015. Materials and methods: Total of one hundred and twenty subjects (n=120)
more » ... subjects (n=120) were divided into two groups. The healthy controls (n=60) were included in group-I whereas patients with chronic renal failure (n=60) were kept in group-II. 5 ml of blood was drawn and sent to laboratory for estimation of serum platelet count, blood urea nitrogen and serum creatinine levels. Results: The present study showed highly significant difference with marked decrease in the platelet counts seen in the CRF patients with 223.9±89.1 million/µL in comparison to the 347.60±55.9 million/µl platelets in control individuals. Also the results of BUN in CRF patients showed highly significant differences with 27.67±7.68 mg/dl when compared to controls having BUN 8.95±1.02 mg/dl. The comparison between GFR with mean platelet count showed negative correlation (r = -0.27) in CRF patients. Conclusion: The present study shows weak negative correlation of platelet count with GFR. Article Citation: Memon S, Kazi N, Fahim A, Nizamani GS, Qureshi A. Chronic kidney disease; the association of platelet count with estimated glomerular filtration rate in known cases. Professional Med J 2016;23 (7) :784-788.
doi:10.17957/tpmj/16.3259 fatcat:xns4tnprhne75kagurqgbz3bx4