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In the present study, the temperature fluctuations in tissues based on Penne's bio-heat transfer equation is investigated by applying the Laplace and Hankel transforms. To get the solution in a physical form, a numerical inversion technique has been applied. The temporal and spatial distribution of temperature is investigated with the effect of relaxation time and is presented graphically.doi:10.2478/ijame-2014-0029 fatcat:hbhqcelo4vcjrflbnjr2vf6q3a