Carbapenem-Resistant Enterobacteriaceae (CRE) Exposure of Hospitals and Nursing Homes From Patients in an Academic Medical Center

Sarah M. Cousins, Kathleen A. Quan, Chenghau Cao, Susan S. Huang
2015 Open Forum Infectious Diseases  
Background. CRE were first detected in CA in 2010. Understanding the emergence of this MDRO due to inter-facility patient-sharing enables targeted interventions for containment. Methods. We identified patients testing positive for CRE between 1 January 2010 and 31 December 2013 at an academic medical center and assessed their demographic characteristics. We then linked patient data to two line-item state hospital and nursing home datasets to capture inter-facility patient sharing and define the
more » ... ring and define the frequency of CRE exposures to other regional facilities. We assessed the number and type of admissions to healthcare facilities in the year prior to and following the confirmed CRE culture. Results. In the four years under study, 54 patients tested positive for CRE and had linked entries in the hospital and nursing home databases (requires SSN). Of the 54 patients, 52% were female with mean age = 66 (SD = 17). In 89%, CRE was found during hospitalization, with mean length of stay (LOS) = 30.7 (SD = 31.9) days. In the year prior to CRE identification, patients visited healthcare facilities 202 times with 1902 hospital days. In the year following diagnosis, 19 (35%) died. These 19 visited 56 facilities and generated 177 CRE-exposure hospital days prior to their deaths. Together,
doi:10.1093/ofid/ofv133.1335 fatcat:ezw6lw6i6vh5rhysiydg5hryme