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Prostate cancer is a leading cause of morbidity and mortality among middle-aged and older men. Of the solid tumors prostate cancer is rather unique in that it presents in 2 distinct forms, a latent form, which grows slowly and poses no threat to the patient's life, and an aggressive form, which metastasizes quickly and kills the patient. The discovery of prostate-specific antigen (PSA) 2 and the demonstration of its utility for early diagnosis and monitoring of prostatic carcinoma have raiseddoi:10.1373/clinchem.2009.140046 pmid:20093554 fatcat:yjlocca7yvdo7kvriemfh7yboy