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Complexity across scales: a walkthrough to linking neuro-imaging readouts to molecular processes
<span title="">2017</span>
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Many histopathological studies have proposed that AD are often related to damage of specific cortical layers such as neocortex and entorhinal cortex [31,32]. The latest MRI techniques still are not capable of examining individual layers of the cortex. However, there are many semi-automated surface reconstruction tools such as FreeSurfer, 3D MPRAGE that aid in cortex examination [33][34][35]. Fractional anisotropy DTI techniques tracts the water diffusion in various tissues which provide vital
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... formation. They help in measuring the structure of white matter as well as fiber connectivity within and across brain regions [36][37][38]. Fractional anisotropy is a numerical measure of fiber integrity. This index is sensitive enough to detect the white matter degradation in aging and other neurodegenerative diseases [39][40][41] (Figure 1 ). Iyappan A (2017) Complexity across scales: a walkthrough to linking neuro-imaging readouts to molecular processes
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