The benefits of primary prevention of colorectal cancer around the age of 20 compared to secondary prevention after the age of 50

Konstantin A Shemerovskii, Petr D Shabanov, Vladimir Ph Mitreikin, Pavel V Seliverstov, Andrei Yu Iurov
2018 Pediatrician (St Petersburg)  
The major advantages of primary prevention of colorectal cancer in young adults (around 20 years) compared with secondary prevention in adults (after 50 years). Primary prevention is aimed at screening and eliminating one of the major proven risk factors for colon cancer - chronic constipation and its predecessor - colorectal bradyarrhythmia - as slower circadian rhythm of defecation. The main advantages of primary prevention of colorectal cancer are: non-invasiveness, safety, efficiency and
more » ... , efficiency and timeliness. Screening of colorectal bradyarrhythmia at 2501 operating physician is allowed to diagnose this arrhythmia in 44% of the surveyed entities. There is discovered the new fundamental dependence between the regularity of circadian rhythm of defecation and an acrophase of this rhythm. The implementation of the morning acrophase of the circadian rhythm of defecation is the key mechanism of the regularity of this rhythm. Repeated screening of colorectal bradyarrhythmia in individuals around the age of 20 years (a month after informing students about the law of circadian rhythm in the brain and intestine) showed that 53% of the students began to observe the morning routine of bowel movements. This led to a transition of moderate stage of colorectal bradyarrhythmia severity (3-4 times a week) in an easy stage (5-6 times a week). It's proved the possibility of primary (behavioral) prevention of colorectal bradyarrhythmia (colorectal coprostasis) as a risk factor for colorectal cancer. Secondary prevention of colon cancer is associated with the invasiveness of colonoscopy, its possible complications (bleeding, perforation of bowel and fatal outcomes), the high cost of special equipment and late in the approach to screening for colorectal cancer (after the appearance of blood in the stool or after 50 years). (For citation: Shemerovsky KA, Shabanov PD, Mitreikin VPh, et al. The benefits of primary prevention of colorectal cancer around the age of 20 compared to secondary prevention after the age of 50. Pediatrician (St. Petersburg). 2018;9(1):17-22. doi: 10.17816/PED9117-22).
doi:10.17816/ped9117-22 fatcat:j6avdhayifc6vk2pjtrtsmo6y4