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Homogeneous and Scalable Gene Expression Regulatory Networks with Random Layouts of Switching Parameters
[article]
2003
arXiv
pre-print
We consider a model of large regulatory gene expression networks where the thresholds activating the sigmoidal interactions between genes and the signs of these interactions are shuffled randomly. Such an approach allows for a qualitative understanding of network dynamics in a lack of empirical data concerning the large genomes of living organisms. Local dynamics of network nodes exhibits the multistationarity and oscillations and depends crucially upon the global topology of a "maximal" graph
arXiv:q-bio/0311031v1
fatcat:iwrzkgu67bb6hakbrgzmraxaau