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The aim of this study was to boost the production rate of a novel thermo-alkalotolerant cellulase (FPase) enzyme from the fungal isolate Aspergillus terreus PPCF. Initially, the extracellular FPase activity was 0.166 ± 0.03 UmL-1 in the culture filtrate, which further increased up to 0.91 ± 0.13 UmL-1 under optimized conditions (3% w/v wheat bran and 0.5% w/v ammonium sulfate). Through response surface methodology, the FPase activity was enhanced to 10.78 UmL1 under the cumulative effect ofdoi:10.35812/cellulosechemtechnol.2020.54.93 fatcat:qognjumvofhvbgdv3kewu3upqe