DIAGNOSTIC ACCURACY OF MAMMOGRAPHY AND MAMMOSCINTIGRAPHY WITH 99M TC-MIBI IN DETECTION OF MINIMAL BREAST CANCER

Antonina Chernaya, Sergey Kanaev, Sergey Novikov, Pavel Krzhivitskiy, Petr Krivorotko, Lyudmila Zhukova, Yekaterina Busko
2017 Voprosi onkologii  
In 437 primary patients with breast cancer (BC) we compared diagnostic accuracy of mammography (MG) and mammoscintigraphy (MCG) with 99mTc-MIBI. All women, included in the study, had lesions suspicious for BC. In 108 suspicious lesions were less than 10 mm in diameter. On histology 33 (30,5%) patients had invasive BC, 20 (18,5%) - noninvasive BC, 6 (5,6%) - lobular carcinoma, 2 (1,9%) - mucinous BC, 8 (7,4%) - fibroadenoma and in remained 39 cases (36,1%) - localised fibrosis. In the group of
more » ... . In the group of women with lesions below 10 mm sensitivity, specificity and accuracy of MG in diagnosis of BC were 72%, 74%, 73%, for MCG - 62%, 51%, 57%. Combination of MG and MCG helped to increase sensitivity to 93,4%. In 53 women with dense breasts sensitivity, specificity and accuracy of MG were 40%, 71,4%, 64%; for mCg two times higher (82%) with specificity of 55% and 60% accuracy. Combination of MG and MCG allowed increasing the sensitivity of diagnosis of minimal BC 2 times more (up to 91%).
doi:10.37469/0507-3758-2017-63-2-274-280 fatcat:jvnaywybjfecfhdco2dohvhire