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Increased urinary or serum concentrations of neopterin have been reported in cancer patients, but less is known about neopterin concentrations in cerebrospinal fluid (CSF). CSF neopterin was determined with radioimmunoassay in 64 patients. CSF neopterin concentrations in patients with tumors were significantly higher compared to patients with predominantly peripheral infections (Lyme borreliosis and herpes simplex infection) and no infectious, inflammatory or neoplastic disorder, anddoi:10.1515/pteridines.2008.19.1.86 fatcat:2amv7db5bnhrvb3qpl5r5ttoji