The anti-inflammatory activity of ethanolic extract of gum Boswellia serrata was determined in carrageenan induced rat paw oedema. The result indicate that ethanolic extract of gum of Boswellia serrata inhibited rat paw oedema significantly (p<0.01) as compared to standard drug Diclofenec sodium (p<0.01) and untreated control group. The present research work is focused to compare herbal extract with allopathic sub. Containing recent NSAID-Diclofenec. Diclofenec was used to test the sensitivity

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... f the system as a standard drug. Topically applied extract will be standardised with physical methods and biological methods. During the physical methods, the following characters were find out of average P H of F1=6.48, F2=7.48 ,Viscosity Of F2 Is 760,000 Centipoises Or 7600 Poise Spread ability of F1=6 and F2= 2.25 Pedal inflammation of control is 0.3±0.0064, F% oedema inhibition is 4 days, F2 % oedema inhibition is 2 days. Granuloma pouch observations were made after 5 days F1=16.12, F2=67.52. Formulation F 2 inhibited oedema formation in formaldehyde induce models of acute inflammation. As compared to the F1 formulation.