Surface Plasmon Spectroscopic Detection of Saxitoxin

Hongxia Chen, Youn Kim, Sam-Rok Keum, Sung-Hoon Kim, Heung-Jin Choi, Jaebeom Lee, Won An, Kwangnak Koh
2007 Sensors  
For the surface-optoelectronic study of Saxitoxin sensing, we fabricated selfassembled calix[4]arene derivative monolayers as the recognition-functional interfaces on a gold surface. An interaction study between Saxitoxin and calix[4]arene derivative monolayers were performed using surface plasmon resonance (SPR) spectroscopy. Among three calix[4]arene derivatives, calix[4]arene crown ether SAM showed the highest sensitivity to Saxitoxin. The detection limit of this system is three orders of
more » ... three orders of magnitude lower than that of the mouse bioassay which is the current benchmark for Saxitoxin detection.
doi:10.3390/s7071216 fatcat:lxjqaxzqfbauniibnsppaytaxi