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Mucosal malignant melanoma of the oral cavity is an extremely rare condition. It has a poor prognosis. Here we report two typical cases of malignant melanoma. In the first case, 64 years old man developed an exophytic tumor in the hard palate. Head and neck and chest computerized tomography scan showed a large aggressive tumor of the hard palate. The patient also had multiple lung metastases and a cervical lymph node. The second case is a 73 years old woman presenting a burgeoning mass on thedoi:10.4236/ijcm.2013.44033 fatcat:wegja2z2jjcrlfseqgwfdrwysi