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Figure S1. The results of R2 and R3 regimen for LM8. Effects of cisplatin (CDDP), 6 mg/kg of body weight, alone or with caffeine (caf) or citrate (CA) at 50 mg/kg or caffeine citrate (cafCA) at 100 mg/kg (R2-chemotherapy) and cisplatin (CDDP), 3 mg/kg of body weight, alone or with caffeine (caf) or citrate (CA) at 100 mg/kg or caffeine citrate (cafCA) at 200 mg/kg (R3-chemotherapy) to treat mice implanted mouse osteosarcoma. Tumor sizes were measured 2 times a week and the volumes calculated,doi:10.6084/m9.figshare.8873783 fatcat:3ohc3cwjarcwdo4s2k7vaes2qa