Changes in T-Cell Homeostasis in Multiple Sclerosis

J Gordon Millichap
2013 Pediatric Neurology Briefs  
Pediatric Neurology Briefs 2013 74 125) and now is associated with development of ASD. Extra-axial fluid and rapid head growth in infancy is not always a benign reversible disorder. Neurobiological abnormalities in infants who later develop ASD. Studies since 2009 showing abnormalities in head circumference, electrophysiological markers and interhemispheric synchronization and differences in various brain regions (amygdala, cerebellum, frontal and temporal cortex) are reviewed by investigators
more » ... d by investigators at the University of Glasgow, Scotland. Cross-disciplinary approaches are essential to elucidate sequence of developmental abnormalities during early infancy leading to ASD (Allely CS, Gillberg C, Wilson P. Behav Neurol 2013 Aug 20. [Epub ahead of print]). Eyeblink conditioning (EBC) is proposed as a non-invasive biomarker for ASD that can be employed shortly after birth (Reeb-Sutherland BC, Fox NA. J Autism Dev Disord 2013 Aug 14. [Epub ahead of print]). The neural circuitry for EBC involves sensory information from the cornea to the trigeminal nucleus, the interpositus nucleus and cerebellar cortex.
doi:10.15844/pedneurbriefs-27-10-2 fatcat:snakg3ejfrah5c3g3cgjlwrle4