Proceedings of the Boston Society for Medical Observation

W. I. RICHARDSON
1875 Boston Medical and Surgical Journal  
of those of diphtheritic endocarditis previously referred to, notwithstanding the absence of that affection -here. Typhoid Fever. -In blood taken from the finger of a typhoid patient in the second week of the disease, Eichhorst1 found fine granular, colorless cells, which were observed for five days. These were from four to six times larger in diameter than the white blood corpuscles, and contained from two to seven yellow disks entirely resembling red blood corpuscles, though somewhat paler.
more » ... h somewhat paler. They could be freed from the larger cells by pressure and the addition of water. Some of the cells presented projections like those of contractile cells. Otherwise the blood was not abnormal ; even the small glistening granules, generally so abundant in febrile blood, were but scanty. Klein " states that he found, in sections from hardened specimens, appearances in the mucous membrane upon and near Peyer's patches which show that an absorption of peculiar organisms occurs, and that they are transmitted along the lymph and blood vessels of the mucous membrane. In a case examined seven days after the headache, peculiar round, yellowish-brown bodies were found in the crypts of Lieberkühn. They varied in size from one fourth to three times that of a human red corpuscle, and were generally grouped in masses, then appearing of an olive-green color ; on the edges of these groups, appearances of subdivision were indicated by kidney and biscuit shaped bodies. Similar bodies were present within the mucous membrane, apparently contained in lymphoid cells. These micrococci were in a genetic relation to a mycelium of a greenish-yellow color. Masses of greenish-yellow micrococci were found penetrating the surface of the mucous membrane from without, also extending from the crypts of Lieberkühn into the surrounding lymph-passages.
doi:10.1056/nejm187504150921504 fatcat:z7caojpt45eldmprmw2mykqvoi