Consolidated bioprocessing for biofuel production: recent advances

Mari Chinn, Veronica Mbaneme
2015 Energy and Emission Control Technologies  
Consolidated bioprocessing (CBP), the combination of saccharolytic enzyme production and secretion, hydrolysis of polysaccharides, and fermentation of available sugars within a single-unit operation, improves cellulose conversion efficiency and decreases lignocellulosic biomass processing costs for producing biofuels and value-added products. Clostridium thermocellum, an anaerobic, thermophilic bacterium is a significant biocatalyst aspirant for CBP, due to its native cellulolytic and
more » ... lytic and ethanologenic capabilities. This review highlights strain development/modification, metabolic engineering, and process improvements associated with CBP in the context of using C. thermocellum as a model biocatalyst to reduce operating expenditures and inhibitory effects for enhanced biofuels production. In addition, opportunities in using a microbial consortia and biofilms are discussed. As an overview of recent advances in CBP technologies to convert lignocellulosic biomass to biofuels, this review gives researchers a platform for future development of efficient and sustainable CBP approaches.
doi:10.2147/eect.s63000 fatcat:e5uej7wv3nbdddsru2qg5fsvam