Introduction and Purpose: Nowadays, the air quality in many major cities is one of the most important environmental problems that seriously compromises the health of residents and causes a range of acute and chronic health effects. Therefore, this study was aimed to quantify and estimate the health effects related to the pollutants NO 2 and O 3 in metropolis of Tehran in 2014 was done by AirQ model. Methods: Data acquired were collected from the environmental organization and the center of air

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... uality control in Tehran. This data were analyzed by Microsoft Excel software, and the processed data was entered AirQ model. The relative risk, baseline incidence and the attributed proportion was estimated and the overall results in case of mortality and morbidity were presented in tables and graphs. Results: The results showed that the average annual concentration of NO 2 and O 3 in Tehran, was respectively 130 and 64 μg/m 3. According to the results with baseline incidence of 543.5 per 100,000, the total cumulative number of mortalities attributed to nitrogen dioxide and ozone, were estimated respectively to be 1593 and 946, that included about 2.66% and 1.58% of total mortalities except traffic accidents in Tehran. Conclusion: Our results showed that the level of air pollution has increased in Tehran, which requires more attention of authorities and policy makers to control the air pollution.