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The principles of the rational pharmacotherapy in pediatric practice are generalized. It should take into account characteristics of pharmacokinetic and pharmacodynamic of drugs influences on the children organism. It is established, that solution of problem for development of high-potent and harmless pharmaceutical forms for children is impossible without including medical, pharmaceutical and regulatory aspects.doaj:08a1bcbbe27c4daca27f19bcff9cd974 fatcat:wcqwfc2jsjbfbfzxmldip2qgqe