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Effect of Cigarette Smoke on Bronchial Reactivity
1995
Canadian Respiratory Journal
OBJECTIVE: To compare the effects of a brief low level exposure to cigarette smoke in rats with known low (Sprague-Dawley) and high (Fisher) airway responsiveness, to test the hypothesis that airways reactivity influences the severity or duration of pulmonary function alterations after cigarette smoke exposure.METHODS: Baseline pulmonary function tests and methacholine dose response tests were conducted in 10 Sprague-Dawley and 10 Fisher rats. On the following day, the animals were
doi:10.1155/1995/502645
fatcat:nrat7vagajay3cinnimwivvub4