A new phenolic glycoside from Lindera nacusua

Jie-Ping Lei, Guo-Qing Wei, Juan-Juan Yuan, Kang-Zhi Tan, Qiao-Yu Chen, Tao Zhang, Chao-Ying Ma, He-Zhong Jiang
2016 Figshare  
The present study was designed to investigate the chemical constituents of Lindera nacusua and their antitumor activities. A new phenolic glycoside, namely 1-O-3-hydroxyphenyl-5-methoxyphenol-(6′-O-vanilloyl)-β-d-glucopyranoside (1), together with five known phenolic glycosides (2–6), two anthraquinones (7, 8) and two γ-butanolides (9, 10), was isolated, and its structure was elucidated by spectroscopic and chemical methods. Compounds 1–10 were screened for their in vitro cytotoxicities against
more » ... HL-60, SMMC-7721, A549, MCF-3 and SW480 cell lines by the MTS method. Compounds 9 and 10 showed moderate cytotoxicities with IC50 values ranging from 17.40 to 35.21 μM.
doi:10.6084/m9.figshare.4214235 fatcat:by4igcfarnaxzoganel2pr26ai