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Platypnea orthodeoxia syndrome (POS) is a rare syndrome traditionally defined as dyspnea or hypoxemia observed when changing from a recumbent to an upright or seated position. A patent foramen ovale (PFO) is oft part of the underlying pathophysiology. Here, a 70-year-old woman with known PFO presents with new symptoms of a platypnea orthodeoxia syndrome. A pulmonary arterial hypertension (PAH), treated with Ambrisentan for years, was also known. In order to clarify the etiology of the newdoi:10.15761/ccrr.1000374 fatcat:nyer34qi6bfahb7bu2pr4eiori