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Journal of Pathology
show an incidence of colorectal cancer some fourfold in excess of Western populations, despite their lower incidence among older age groups. We have already shown that in Western patients 35 years of age or younger 58% have the RER+ phenotype and 42% have germ-line mutations in Msh2, whilst in turnours from young Hong Kong Chinese, the proportion of RER+ tuinours is very similar (62%), 55% of the RER+ tumours having gemline mutations in Msh2 Comparative genomic hybridisation (CGH) was applieddoi:10.1002/path.1711900102 fatcat:ixrzp5vhunbxnguvoasez3c2ii