Withdrawal seizure associated with high dosage of aripiprazole and fluoxetine: a case report

Jian-An Su, Shih-Yong Chou, Ching-Shu Tsai, Tai-Hsin Hung
2011 Open Journal of Psychiatry  
Aripiprazole, a third-generation antipsychotic, has been considered to have a high safety profile and rare withdrawal symptoms. We reported the case of a schizophrenic patient with a significant obsession, who was treated with a high dosage of aripiprazole and fluoxetine. Generalized tonic-clonic seizure occurred two days after abruptly stopping these two medications. Gradually tapering aripiprazole is suggested in clinical practice, especially when using a high dosage.
doi:10.4236/ojpsych.2011.12005 fatcat:f52v57exvra7jb5dtzcs2smohu