Draft a protocol for a superiority phase III RCT for assessing the effectiveness of Fampridine in Multiple Sclerosis [article]

Μαρία-Δέσποινα Παραφέστα, Χρυσούλα Δοξάνη, University Of Thessaly, University Of Thessaly
2020
Study Title This is a randomized, multicenter, placebo-controlled, double-blind, phase III clinical trial to evaluate the efficacy of Fampridine in Multiple Sclerosis (MS). Study Objectives The primary objective of the study is to evaluate the efficacy and safety of extended-release Fampridine in the treatment of motor dysfunction in adult patients with multiple sclerosis. Primary Endpoint The proportion of patients who experience a steady improvement in walk speed during treatment, as will be
more » ... atment, as will be measured by the 25-foot timed walking test (T25FW, Timed 25-foot Walk).
doi:10.26253/heal.uth.7371 fatcat:elkjazfivra3nlgx4tazupoyla